Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

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Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

BACKGROUND Usefulness of next-generation sequencing (NGS) in assessing bacteria associated with oral squamous cell carcinoma (OSCC) has been undermined by inability to classify reads to the species level. OBJECTIVE The purpose of this study was to develop a robust algorithm for species-level classification of NGS reads from oral samples and to pilot test it for profiling bacteria within OSCC ...

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Title MetaCluster 4 . 0 : A novel binning algorithm for NGS reads andhuge number of species

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ژورنال

عنوان ژورنال: Journal of Oral Microbiology

سال: 2015

ISSN: 2000-2297

DOI: 10.3402/jom.v7.28934